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Do Methotrexate side effects get better? Many patients on methotrexate have few or no side - effects. Among those who do have problems, most side - effects resolve by lowering the dose or, if needed, discontinuation of the drug. But your dose should never be lowered - nor discontinued - without the guidance of your physician.
Can methotrexate cause extreme tiredness? Many also complain of headaches, fatigue and an overall "blah" feeling – sometimes called " methotrexate fog" – that can occur a day after receiving a dose of methotrexate (which is taken in pill form or injected once a week).
Is Methotrexate covered by insurance? It is only available as a generic drug; all brands have been discontinued. Generic methotrexate is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
How long after taking methotrexate Do side effects start? Like all DMARDs, Methotrexate takes time to work. Most patients start to feel the positive effects of methotrexate at 4-8 weeks, with maximum benefit at 3-6 months. Side effects can occur earlier.
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